Sapogenins fromHedera pastuchovii

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Saponins and Sapogenins

The seeds of Luffa aegyptica Mill, locally known as "ghia torai" (family Cucurbitaceae), have earlier been studied for the saponin and sapogenin contents and found to contain a mixture of colourless saponins which on hydrolysis yields two acid and a neutral sapogenin. The acetates of the two acid genins melted at 266-268" and 176-181" while the neutral genin acetate melted at 262-264O.l The aci...

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Saponins and Sapogenins from Brachiaria decumbens Stapf

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Preliminary pharmacobiological study of new steroidal sapogenins.

The chemotherapeutic study of a limited series of steroidal sapogenins from several endemic species of the flora of the Canary Islands is presented here. On the whole, they possess a very weak antibacterial activity, a slight antifungal effect and one of them, vespertilin, displays interesting cytostatic activity (ID50 = 5 micrograms/ml). A pharmacodynamic screening carried out on this product ...

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Triterpene sapogenins with oleanene skeleton: chemotypes and biological activities.

Critical survey of a selected class of pentacyclic triterpenes--the oleanane family, is presented based on current literature in order to underline their value for medicinal chemistry and drug development potential. Oleanenes may be considered as a renewable resource of valuable research materials which are structurally diverse, inherently biocompatible and have built-in affinity for many categ...

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Effect of steroidal sapogenins on ruminal fermentation and on production of lactating dairy cows.

Supplementation of dairy rations with steroidal sapogenins was evaluated in an in vitro, an in situ, and a production trial. Sixteen in vitro semicontinuous rumen cultures were supplied a 55:45 concentrate to roughage substrate with Sarsaponin concentrations of 0, 33, 55, and 77 ppm of air-dry feed for 22 d. Supplementation decreased protozoa numbers and increased bacterial numbers and acid det...

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ژورنال

عنوان ژورنال: Chemistry of Natural Compounds

سال: 1970

ISSN: 0009-3130,1573-8388

DOI: 10.1007/bf00567339